Amino acid dysregulation metabotypes: potential biomarkers for diagnosis and individualized treatment for subtypes of autism spectrum disorder
ASD is currently diagnosed based on behavioral characteristics exhibited by an affected child. While specialist clinicians are able to confidently diagnose children as young as 24 months, the average age of diagnosis in the United States is over 4 years. Families often experience long waits to receive a definitive diagnosis due to the paucity of trained clinicians able to perform diagnostic assessment. Early diagnosis is important because intensive behavioral therapies are not only effective in reducing disability in many children with autism, but, the benefit of early intervention is greater the earlier the intervention is started.