Presented at the 2019 Annual Meeting of the International Society for Autism Research in Montreal, Ontario, Canada in May 2019.

The Children’s Autism Metabolome Project (CAMP, ClinicalTrials.gov: NCT02548442) recruited 1,100 children for metabolomic analyses to identify altered metabolism associated with ASD. Previous research identified ASD subjects associated with branched-chain amino acid (BCAA) dysregulation. With this second look at the data, our goals are to create metabolism-based diagnostic tests based on reproducible metabotypes and to examine the overlap of biochemical processes associated with metabotypes. Overall, biological processes associated metabotypes were identified in 41% of CAMP ASD subjects.