Identification of Neurotransmitter-Associated and Other Metabotypes: Further Stratification of the Children’s Autism Metabolome Project (CAMP) ASD Subjects – INSAR 2019 [PDF]
Presented at the 2019 Annual Meeting of the International Society for Autism Research in Montreal, Ontario, Canada in May 2019.
The Children’s Autism Metabolome Project (CAMP, ClinicalTrials.gov: NCT02548442) recruited 1,100 children for metabolomic analyses to identify altered metabolism associated with ASD. Previous research identified ASD subjects associated with branched-chain amino acid (BCAA) dysregulation. With this second look at the data, our goals are to create metabolism-based diagnostic tests based on reproducible metabotypes and to examine the overlap of biochemical processes associated with metabotypes. Overall, biological processes associated metabotypes were identified in 41% of CAMP ASD subjects.
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