Identification of Neurotransmitter-Associated and Other Metabotypes: Further Stratification of the Children’s Autism Metabolome Project (CAMP) ASD Subjects

Presented at the 2019 Annual Meeting of the International Society for Autism Research (INSAR) in Montreal, Ontario, Canada in May 2019.

The Children’s Autism Metabolome Project (CAMP), ClinicalTrials.gov: NCT02548442, recruited 1,100 children for metabolomic analyses to identify altered metabolism associated with ASD. Previous research identified ASD subjects associated with branched-chain amino acid (BCAA) dysregulation. With this second look at the data, our goals are to create metabolism-based diagnostic tests based on reproducible metabotypes and to examine the overlap of biochemical processes associated with metabotypes. Overall, biological processes associated metabotypes were identified in 41% of CAMP ASD subjects.

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