Metabolism-Based Diagnosis and Precision Medicine for Autism Spectrum Disorders [National TACA Autism Conference – East Coast 2019]
Presented at the National TACA Autism Conference – East Coast in Atlanta, Georgia; March 2019.
We conducted the Children’s Autism Metabolome Project (CAMP), the largest clinical study to date of the metabolism of children with autism spectrum disorder (ASD). Utilizing our proprietary analysis methods to analyze the metabolism of these 1,100 children, ages 18-48 months, we created very precise tests which identify unique subtypes of metabolism in children with ASD. We recently published (Smith et al., 2018) some of these subtypes associated with dysregulation of amino acids and branched-chain amino acids. Metabolism-based stratification of ASD offers the potential for earlier diagnosis and more precise interventions, based on the child’s own metabolism.
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